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Literature summary extracted from

  • Retzios, A.D.; Markland, F.S.
    Fibrinolytic enzymes from the venoms of Agkistrodon contortrix contortrix and Crotalus basiliscus basiliscus: cleavage site specificity towards the alpha-chain of fibrin (1994), Thromb. Res., 74, 355-367.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.72 Agkistrodon contortrix contortrix
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.72 venom
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Agkistrodon contortrix contortrix
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.72 Fibrinogen Aalpha-chain + H2O cleavage at Lys413-Leu414 (initial cleavage) Agkistrodon contortrix contortrix ?
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3.4.24.72 Fibrinogen Aalpha-chain + H2O cleavage specificity is not dictated by the Lys-Leu bond per se, but by the surrounding sequence Agkistrodon contortrix contortrix ?
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